Guidewave has further products in development which will enable an alternative route of infusion directly down the guide catheter:
There is a procedural challenge to infusing directly down a guide catheter whist simultaneously displaying real time pressure. Infusion down the guide catheter changes the aortic pressure reading, thus affecting the FFR calculation.
This challenge is compounded by the fact that flow rate needs to be high enough to get sufficient drug rapidly into the coronary arteries, but pressure difference rises as infusion rate is increased. At a clinically useful infusion rate, the resulting FFR inaccuracy would be unacceptable and could contribute to inappropriate patient management.
Guidewave’s future products are designed to address this challenge easily in routine practice by integrating and automating flow compensation.